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| 12:00 PM | Eastern Kentucky at No. 8 Louisville |  |
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| 12:00 PM | No. 12 Florida at Miami (FL) |
 
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| 12:00 PM | No. 13 Oklahoma State at UTSA | FOX Sports 1 | |||
| 12:00 PM | Tennessee Tech at No. 21 Wisconsin | Big Ten Network | |||
| 12:00 PM | Southeastern Louisiana at No. 24 TCU | ||||
| 12:00 PM | Miami (OH) at Kentucky | |
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| 12:00 PM | South Florida at Michigan State |
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| 12:00 PM | Norfolk State at Rutgers | CBS Sports Network | |||
| 12:00 PM | Eastern Michigan at Penn State | Big Ten Network | |||
| 12:00 PM | Houston at Temple | |
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| 12:00 PM | Cincinnati at Illinois |
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| 12:00 PM | Missouri State at Iowa | Big Ten Network | |||
| 12:00 PM | Bowling Green at Kent State | |
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| 12:00 PM | Indiana State at Purdue | Big Ten Network | |||
| 12:21 PM | Western Kentucky at Tennessee | |
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| 12:30 PM | South Carolina State at No. 4 Clemson | |
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| 12:30 PM | Middle Tennessee at North Carolina | |
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| 1:00 PM | Army at Ball State | |
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| 1:30 PM | Western Carolina at Virginia Tech | |
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| 2:00 PM | Maine at Massachusetts | |
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| 2:00 PM | Weber State at Utah | Pac-12 Network | |||
| 2:00 PM | Chattanooga at Georgia State | |